Rheumatoid Arthritis Study

To enable us to assess your suitability for upcoming clinical trials please answer the following questions:


Are you between the ages of 18-65


Have you been diagnosed with Rheumatoid Arthritis at least for 6 months


Do you have joints that are painful, swollen, inflamed or stiff in the morning


Taking Methotrexate weekly and/or taking Methorexate plus 1 biologic weekly and it does not help



Rheumatoid arthritis is an autoimmune disease. If left untreated the disease can lead to the destruction of joints along with chronic pain, loss of strength and function and the ability to perform normal daily activities.

What causes rheumatoid arthritis?

There is a lot of uncertainty around the exact underlying causes of rheumatoid arthritis.

We know that it is an autoimmune disease. The immune system that normally protects the body against infections and other diseases attacks the joints. The bad side of rheumatoid arthritis is that it affects more than just the joints. It is a systemic disease that also increases your risk for cardiovascular diseases, certain lung conditions as well as causing unnatural tiredness and a constant feeling of being sick.

Even though we cannot predict who will get rheumatoid arthritis, we do know that certain characteristics increase a person’s chance of developing rheumatoid arthritis. This includes: family history of the disease, being overweight, smoking, bad oral hygiene, gender (more women get the disease than men), age (it is the most common amongst people between the ages of 30-50) but can happen at any time. It is also more inclined to happen shortly after giving birth.

What are the typical symptoms?

Classic symptoms include:

  • Stiffness – usually in the morning and lasts for a long time, longer than 1 hour
  • Swelling and pain of the affected joint that often starts in the hands but can affect any joint

The joints can also be red and feel warm.

The medicines that are used to treat the disease and to minimize damage are called anti-rheumatic drugs (DMARDS is the abbreviation). Anti-inflammatory pain medication and cortisone are used to provide temporary relief from the symptoms but unfortunately do not prevent long term damage that is caused by the disease.

Male and Female
Rheumatoid Arthritis

As one of the largest and most recognised clinical study organisations in the world, Synexus provides a friendly relaxed environment where you have the opportunity to help others and maybe also yourself. A clinical trial offers an opportunity to help researchers find better treatments for others in the future.

All Synexus studies are approved by SAHPRA an independent ethics committee.

Recruiting at the following locations

Helderberg Clinical Research Centre: Somerset West Quick view
Watermeyer Clinical Research Centre: Pretoria Quick view
Stanza Clinical Research Centre: Mamelodi Quick view

Still unsure?

Feel free to call us on 0861 796 398 to find out more about this study.


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